Mitochondria in 3D

Electron Tomography

Mitochondrial Structure in Apoptosis

Bamboo-greengray90x90

Electron tomography allows us to see the 3D structure of mitochondria. (see our publication: von Ahsen et al., 2000; from a collaboration with Guy Perkins and Mark Ellisman at UC San Diego).

collage_image
An Untreated Mitochondrion (click to view movie)
collage_image
A mitochondrion treated with the pro-apoptotic protein tBid. Note that the structure is essentially the same as the untreated mitochondrion.
collage_image
A mitochondrion treated with calcium. Note the swollen matrix.